“We can alleviate physical pain but mental pain … dementia is less accessible to treatment. It’s connected to who we are – our personality, our character, our soul …” Richard Eyre

This book is about what causes Alzheimer’s, autism, and stroke and how you and your loved ones can avoid and prevent these terrible diseases. Based upon the latest scientific literature and annotated with references to that literature, this book introduces you to aluminum being the primary culprit that causes Alzheimer’s, autism, and stroke. Specific methods are given for lowering your aluminum ingestion and enhancing your aluminum excretion. Secondary culprits such as genetics, vitamin and folic acid deficiency, LDL, triglycerides, atrial fibrillation, and lifestyle choices are also covered. A preventative system is proposed for individuals involving 7 supplements, 7 lifestyle choices, and a dissolved mineral that will prevent Alzheimer’s, autism, and stroke. This is also a combination therapy that can reverse the cognitive decline in early stage Alzheimer’s disease. Recently a combination therapy involving 6 of the 7 supplements and 2 of the 7 lifestyle choices was tested on a limited population of 10 Alzheimer’s patients. The 9 early stage AD patients all showed improved cognition in the first 3 to 6 months of treatment. All six of the patients whose cognitive decline had a major impact on job performance returned to work during the study (Ref. 536).

Alzheimer’s, autism, and stroke may be thought of as both modern diseases and mismatch diseases. This is because these diseases resulted from behaviors and cultural practices that have changed both our environment and lifestyles making them more harmful than what our ancestors experienced during their evolution. Information is frequently the catalyst for cultural modification and hopefully the information in this book will facilitate a cultural change in behaviors that will ultimately prevent mismatch diseases, such as Alzheimer’s, autism, and stroke. Individually and collectively we can change our culture and make the choice to prevent these mismatch diseases with the following recommendations:  

Recommendations for Preventing Alzheimer’s, Autism, and Stroke

Seven Supplements:

1. PQQ: Protect your brain during and after a stroke, increase the energy available in your brain, and enhance your memory and keep your brain young with more neurites by taking a PQQ supplement (20mg/day).

2. CoQ10: Protect your brain during and after a stroke from oxidative stress and increase its energy efficiency by taking a CoQ10 supplement (ubiquinone 200mg/day).

3. Vitamin D3: Lower aluminum levels in your blood and tissues and maintain healthy levels of glutathione and low levels of inducible nitric oxide synthase prior to age 71 with 600 IU or over age 71 with 2,000 IU’s of supplemental D3. In order to protect the fetus and infant from aluminum, mothers are recommended to take 4,000 IU/day while pregnant and 6,000 IU/day of vitamin D3 while breastfeeding. Infants should be given 400 IU/day and children should be given 800 IU/day of vitamin D3. If baby formula is used it should have a sufficient level of vitamin D3 to correspond to 400 IU/day based upon the volume of formula the infant consumes, otherwise vitamin D3 supplementation is recommended.

4. Taurine: Protects your brain during and after a stroke and lowers the risk of stroke with a taurine supplement (500mg/day). Taurine crosses the blood-brain barrier and ameliorates the toxic effects of aluminum and other metals in the body.

5. Vitamin K2-MK-4: Prevents and possibly reverses aortic mitral valve calcification. Take a daily supplement of vitamin K2-MK-4 (500mcg/day) and vitamin K2-MK-7 (100mcg/day) for cardiovascular health. For osteoporosis take K2-MK-4 (5mg/day). Do not take these supplements if you are taking oral anticoagulants, like warfarin (a.k.a. Coumadin), that are vitamin K antagonists.

6. B100 Supplement: Keeps your homocysteine levels low (100mg/day of vitamin B6, 100mcg/day of vitamin B12, and 400mcg of folic acid). These are all found in a time-release B100 complex. In the case of vitamin B12 malabsorption, use sublingual absorption tablets containing B12, B6 (as pyridoxine hydrochloride), folic acid and biotin from Wonder Laboratory or get B12 shots from a doctor.

7. 5-MTHF (Methyl Folate): Take 400mcg/day of 5-MTHF in order to keep your homocysteine levels low, even if you have the MTHFR gene that prevents your body from converting folic acid to methyl folate.

Seven Lifestyle Choices:

1. Stop smoking – in order to lower aluminum and homocysteine levels and risk of stroke.

2. Decrease alcohol consumption – in order to lower homocysteine levels and risk of stroke.

3. Avoid aluminum ingestion

 Avoid aluminum containing pharmaceuticals – Read labels and lists of ingredients. Do not use antacids containing aluminum
 Filter your drinking water – Use a Brita pour-through pitcher system with filter number OB03 to remove aluminum from your tap water.
 Avoid using aluminum cookware – Use stainless steel and cast iron for cooking. Use non-stick aluminum foil with the non-stick surface against food or use a layer of plastic wrap between aluminum foil and food.
 Use aluminum free antiperspirants and astringents – Use either Arm & Hammer’s “Essentials” or Tom’s of Maine “Original” deodorants that are both aluminum free. Use Epsom salts and avoid aluminum containing astringents for mild skin irritation.
 Don’t purchase and store beverages or food in aluminum containers – as they will slowly add aluminum to the water and beverages. Purchase and store beverages and food in glass or plastic.
 Avoid using soy-based infant formula – Purchase non-soy based formula.

4. Increase dissolved silica in your diet – Eat food and drink beverages high in silica.

5. Aerobically exercise – Exercise for 40 minutes at least three times a week at 60 to 75% of your heart rate reserve for the following benefits:

• Results in the destruction and clean-up of amyloid plaque in the brain
• Increases neurogenesis in the dentate gyrus of the hippocampus resulting in larger hippocampal volume and increased memory
• Stimulates production of PYY that lowers aluminum absorption and accumulation.
• Reverses the effect of aluminum in the prefrontal cortex thereby improving working memory
• Increases aluminum excretion by perspiration facilitated by a diet including a mineral water with dissolved silicic acid.

6. Avoid lack of sleep – Get exposure to sunlight or blue light every day to maintain your circadian rhythm.

7. Avoid head trauma – Avoid head trauma by using walking and balance aids, wear a seat belt, wear a helmet on a bike, and remove obstacles on the floor of walkways.

Take the Dissolved Mineral OSA Daily:

Take three to four cups of high silica mineral water, such as Fiji Water or homemade Silicade. The recipe for Silicade is in Chapter 5. Or take a dissolved silica (OSA) supplement containing 10 to 34mg of silicon daily. For example take 5 drops of choline stabilized orthosilicic acid (a.k.a. Biosil) twice a day in a quarter cup of flavored liquid to increase aluminum excretion by your kidneys. Silica supplementation is also recommended for children.

Cultural and Governmental Changes:

1) Encourage your local community’s water department to maintain at least 10mg/liter OSA (i.e. soluble silica) in drinking water. This will decrease aluminum accumulation in your and your children’s brains. Silica also protects water pipes from corrosion (PQ Corp., Bulletin 37-3).

2) Encourage your local community’s water department to cease adding fluoride to drinking water. This will both decrease aluminum corrosion while cooking in aluminum cookware and will decrease accumulation of aluminum in the brains of those who drink the water.

3) Encourage more government funded research to develop non-aluminum adjuvants for vaccines.

4) Have your child vaccinated with one vaccine at a time. This may require the use of the federal government’s Vaccine Injury Compensation Program (VICP). In a landmark case in 2008 the Poling family was awarded damages under VICP when their daughter Hannah developed autism-like symptoms after the administration of vaccine.

5) When a choice is available, as in the case with Hib and Hepatitis A and B, use vaccines with aluminum hydroxide and not aluminum phosphate or alum as an adjuvant. Although all aluminum containing adjuvants are bioavailable, aluminum hydroxide has been shown to be less bioavailable than other aluminum adjuvants.

6) Encourage the labeling of all food and pharmaceutical products that contain aluminum as a food additive, inactive ingredient, or active ingredient. The warning label should both state that the product contains aluminum and that aluminum is a known neurotoxin causing Alzheimer’s, autism, and stroke.

7) Encourage the labeling of all food, including baby formula, with the amount of aluminum per serving. This will allow producers of baby formula with low aluminum levels to differentiate their formula from other brands with higher aluminum levels.

8) Encourage the sale of baby formula fortified with dissolved or dissolvable silica, and PQQ as found in mother’s milk. Producers of baby formula should find the addition of silica, and PQQ as a way to differentiate their baby formula from others on a crowded shelf of competing baby formulas in the market.

9) Encourage our government to change the current standard for intravenous feeding solutions (e.g. parenteral nutrition) used with premature babies, limiting the aluminum in these solutions to less than 0.1mcg/liter. This is the calculated average concentration of aluminum absorbed into the infant’s blood when being fed breastmilk.

10) Encourage our government to adjust the current aluminum U.S. MRL standard to lower levels due to aluminum being a causal factor of Alzheimer’s, autism, and stroke. Different MRL standards are required for infants and children, with developing brains, pregnant women, and other adults.

Miscellaneous Recommendations:

1) Get your homocysteine and B12 blood levels tested yearly.

2) Take zinc chelated with an amino acid (15mg/day) and N-acetylcysteine (NAC, 600mg/day) in order to keep your blood-brain barrier healthy by combating aluminum and increasing glutathione (see Appendix V).

3) Take a statin to lower your LDL and decrease the risk of stroke, if LDL or total serum cholesterol level is too high and you have not had a prior hemorrhagic stroke. Otherwise take chromium picolinate (200mcg/day) to lower your LDL.

4) Eat a diet high in omega-3 fatty acids, as described in the section on DHA in Chapter 3, and take a quarter gram per day of the omega-7 palmitoleic acid, if your serum triglyceride level is too high.

5) Take 1 to 2 grams of EPA supplement every day and a quarter gram per day of the omega-7 palmitoleic acid, if both your serum triglyceride and LDL levels are too high.

6) Take DHA (1 gram/day) or a mixture of DHA and EPA (1 gram/day), if your memory becomes impaired due to poor diet,

7) Use toothpaste not packed in aluminum lined tubes (i.e. Toms of Maine), or packed in tubes with a layer of plastic between the toothpaste and aluminum (i.e. Crest, Colgate).

8) Do not swallow toothpaste with fluoride during use.

9) Avoid using food products containing alum (i.e. some baking powders, baking mixes, shredded cheeses, and pickles).

10) Use homemade baking powder that contains less than 4mcg per teaspoon of aluminum. Made from cream of tartar, baking soda, and corn starch.

11) Use table salt, such as Morton, that is aluminum free.

12) Lower your stress and caffeine intake – 12oz. of coffee contains 200mg. of caffeine.

13) Lower aluminum intake by minimizing green and black tea and chocolate.